Ribosome P0


Ribosome P Protein (RPP) antibodies target the phosphoproteins P0 (38 kD), P1 (19 kD) and P2 (17 kD) of the 60S subunit of the ribosomal complex. RPP antibodies are detected in 10-35 % of SLE patients and have high specificity (99 %) and positive predictive value. Their detection in patients suffering from other autoimmune diseases may be a sign of SLE overlap. Moreover RPP antibodies were shown to be associated with disease activity and particular organ involvements (Nephritis, Liver manifestations).  


Antigen used by D-tek

Recombinant human, expressed in Baculovirus-infected Sf9 cells (for more information on our antigens click here)