The H+/K+ ATPase is a membrane enzyme which catalyzes the counter transport of H+ and K+ and is responsible for the acidification of the stomach.

Parietal Cell Antibodies (PCA) target H+/K+ ATPase and can be detected in 80-90% of Type A Chronic Atrophic Gastritis patients, from early stages to Pernicious Anaemia. They are also detected in 2-5 % of the adult healthy population.


Antigen used by D-tek

Purified from porcine gastric mucosa (for more information on our antigens click here)